Xiaoyong Ren

Ren Xiaoyong, Director, senior doctor, professor, doctoral supervisor of Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Xi 'an Jiaotong University. Graduated from the Medical Department of Xi 'an Medical University in 1993 and received the ph. D. degree in 2005. Continuing Education in head and neck Surgery in National Cancer Center of Japan in 2012.

Academic membership:

l Membership: otolaryngology Head and Neck Surgery Branch of Chinese Medical Association, Voice Medicine group

l Membership: otolaryngology Head and Neck Surgery Branch, Chinese Medical Doctor Association, head and neck Oncology Group

l Membership: Sleep Medicine Special Committee of Chinese Medical Doctor Association, Deputy leader of Otorhinolaryngology Head and Neck Surgery Group

l Membership: Chinese Sleep Research Association

l Membership: Shaanxi Cancer Medicine Association

l Chairmanship: head and neck Tumor Professional Committee of Shaanxi Cancer Medicine Association

l Chairmanship: Sleep Medicine Professional Committee of Shaanxi Medical Doctors Association

l Editorship: Otolaryngology head and Neck Surgery, textbook for standardized training of National resident training

Research Fields:

l Clinical and basic research on head and neck cancer and voice diseases

l Pathology and clinical comorbidity of sleep apnea

Expertise:

l Surgery and comprehensive treatments of Laryngopharyngeal head and neck tumors

l Multidisciplinary diagnosis and surgical treatment of OSAHS in adults and children

l Minimally invasive treatment of voice diseases

Achievements:

l national and provincial projects: 7

l provincial science and technology awards: 2

l national invention patents: 3

l Academic papers: more than 100 (including 30 of SCI papers)

Representative papers:

1. Zhu K, Xia C, Chen J, Yu C, Gao T, Yan J, Shao N, Zhu P, Sun B, Ren X, Zhang Y.Serum Soluble ST2 Correlated with Symptom Severity and Clinical Response of Sublingual Immunotherapy for House Dust Mite-Induced Allergic Rhinitis Patients Mediators Inflamm . 2021 May 30;2021:557-596.

2. Shi Y, Zhang Q, Xie M, Feng Y, Ma S, Yi C, Wang Z, Li Y, Liu X, Liu H, Yang H, Yan Y, Zhang Y, Ren X, Luo H. Aberrant methylationmediated decrease of lncRNA HNF1AAS1 contributes to malignant progression of laryngeal squamous cell carcinoma via EMT. Oncol Rep. 2020 Dec;44(6):2503-2516.

3. Luo J, Liu H, Gao X, Wang B, Zhu X, Shi Y, Hei X, Ren X. A novel deep feature transfer-based OSA detection method using sleep sound signals. Physiol Meas. 2020 Aug 11;41(7):075009. doi: 10.1088/1361-6579/ab9e7b.

4. Shi Y, Luo H, Liu H, Hou J, Feng Y, Chen J, Xing L, Ren X. Related biomarkers of neurocognitive impairment in children with obstructive sleep apnea. Int J Pediatr Otorhinolaryngol. 2019 Jan;116:38-42.

5. Hua-Nan Luo, Qi-Mei Yang, Ying Sheng, Zheng-Hui Wang, Qing Zhang, Jing Yan, Jin Hou, Kang Zhu, Ying Cheng, Bo-Tong Wang, Ying-Long Xu, Xiang-Hong Zhang, Min Xu, Xiao-Yong Ren. miR-139 targets CXCR4 and inhibits the proliferation and metastasis of laryngeal squamous carcinoma cells. Med Oncol, 2014, 31 (1): 789.

6. Fei Zhao, Weiwei Huang, Tamgue Ousman, Bin Zhang, Yangyang Han, Daguia Zambe Johh Clotaire, Chen Wang, Huanhuan Chang, Huanan Luo, Xiaoyong Ren, Ming Lei. Triptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by causing p53 activitiy via suppression of the E6-mediated P53 degradation. Plos one, 2013; 8(11): e80784.

7. Hua-Nan Luo, Zheng-Hui Wang, Ying Sheng, Qing Zhang, Jing Yan, Jin Hou, Kang Zhu, Ying Cheng, Ying-Long Xu, Xiang-Hong Zhang, Min Xu, Xiao-Yong Ren. Role of pepsin and pepsinogen: Linkin3g laryngopharyngeal reflux with otitis media with effusion in children. Laryngoscope, Laryngoscope 2014 Jul;124(7):E294-300. doi: 10.1002/lary.24538. Epub 2014 Jan 15.

8. Jiang X, Ren X, Liu H, Tian J, Du C, Luo H, Cheng Y, Shang L. Health-related quality of life among children with adenoid hypertrophy in Xi'an, China. Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2321-6.

9. HuaNan Luo , Yuan Jiang , SiJing Ma , HuanHuan Chang , ChunXi Yi , Hui Cao , Ying Gao , HaiLi Guo , Jin Hou , Jing Yan , Ying Sheng , XiaoYong Ren .EZH2 promotes invasion and metastasis of laryngeal squamous cells carcinoma via epithelial-mesenchymal transition through H3K27me3. Biochem Biophys Res Commun. 2016 Oct 14;479(2):253-259. doi: 10.1016/j.bbrc.2016.09.055. Epub 2016 Sep 13.

10. Yewen Shi, Yani Feng, Yitong Zhang, Haiqin Liu, Huanan Luo, Lei Shang, Liang Xing, Jin Hou, Jing Yan, Xiaohong Liu, Qingqing Zhang, Chao Si, Xiaoyong Ren. Assessment of event-related evoked potentials and China-Wechsler intelligence scale for cognitive dysfunction in children with obstructive sleep apnea. Int J Pediatr Otorhinolaryngol,2021Aug24;150:110901. doi: 10.1016/j.ijporl.2021.110901. Online ahead of print.