Qiang Huang

Qiang Huang, M.D., Ph.D.

Professor of Pediatric Surgery, Attending Doctor

The Second Affiliated Hospital of Xi’an Jiaotong University

Xi’an, Shaanxi, China

Email: drhuang@xjtu.edu.cn

I graduated from Xi’an Jiaotong University in 2013 and became a pediatric surgeon in the Second Affiliated Hospital of Xi’an Jiaotong University. I obtained and completed two grants from China National Science Foundation as a principal investigator. In 2017, I entered Xiling Shen’s Lab in the Department of Biomedical Engineering at Duke University. I was elected to the “Young Talent Support Plan” of Xi’an Jiaotong University in 2020.

I have published 20 papers in prestigious journals, including Science, Cell Stem Cell, Nature Communications, Advanced Science, light: science and applications, IEEE transactions on Medical Imaging, Cellular and Molecular Life Science, and Cellular signaling.

With the advantage of the multidisciplinary team in Shen lab and my background in the study of embryonic development, I developed a novel intravital imaging method that allows the in uterus imaging of mouse embryos from E9.5 to birth. We used several fluorescence labelled mouse strains, or interspecies chimeras to visualize protein localization and cellular dynamics to demonstrate the utility of this new technique. With combing with various tissue manipulation and microscopy methods, this method provides a powerful tool for understanding the processes of post-implantation development at unprecedented patiotemporal resolution. This technique is an exciting technical advance for this field and will have broad applications in neuroscience, developmental biology and embryology. This exciting study was published in Science in 2020.

My research focuses on the developmental system and we will use our developed techniques to better understand the complexity of different organs during the process of development from embryos to adults. We are using transgenic mice to investigate how different types of cells give rise to the emergent properties of organisms. There are two areas of interest: 1) Lineage tracking for individual cells; 2) Tracking how the microenvironment interacts with the individual cells to give rise to the emergent properties of organisms. We are also creating new human-mouse chimeras to investigate the specific integration processes that occur during growth and aging, with a focus on understanding how the niche affects the specific cells during embryogenesis.

Welcome to join us!